Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 5/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | MAOB | P27338 | 5/20 | 0.55 |
| ▸ | DAO | P14920 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724983 | 1.00 | AOC2 (0.55) | AOC2MAOAMAOBDAOAOC3 | |
| SCHEMBL10722411 | 1.00 | AOC2 (0.55) | AOC2MAOAMAOBDAOAOC3 | |
| Ammonia Solution, Strong SCHEMBL11133049 | 0.98 | AOC2 (0.53) | AOC2MAOAMAOBDAOAOC3 | |
| Ammonia Solution, Strong SCHEMBL11133048 | 0.98 | AOC2 (0.53) | AOC2MAOAMAOBDAOAOC3 | |
| SCHEMBL1295183 | 0.89 | AOC2 (0.49) | AOC2MAOAMAOBDAOAOC3 | |
| SCHEMBL1295225 | 0.89 | AOC2 (0.49) | AOC2MAOAMAOBDAOAOC3 | |
| SCHEMBL1295180 | 0.89 | AOC2 (0.49) | AOC2MAOAMAOBDAOAOC3 | |
| Hydrochloric Acid SCHEMBL1295025 | 0.87 | AOC2 (0.47) | AOC2MAOAMAOBDAOAOC3 | |
| Hydrochloric Acid SCHEMBL1295029 | 0.87 | AOC2 (0.47) | AOC2MAOAMAOBDAOAOC3 | |
| SCHEMBL27912802 | 0.85 | CES1 (0.46) | AOC2MAOAMAOBDAOCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067105-B1 | ALLYL AMINE MAO INHIBITORS | MERRELL DOW FRANCE ET CIE (FR) | 1987-09-23 | — | — | EP | claimed |
| US-4454158-A | Allyl amine MAO inhibitors | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-12 | — | — | US | claimed |
| EP-0067105-A2 | Allyl amine MAO inhibitors | MERRELL DOW FRANCE ET CIE (FR) | 1982-12-15 | — | — | EP | claimed |
| EP-0067105-B1 | ALLYL AMINE MAO INHIBITORS | MERRELL DOW FRANCE ET CIE (FR) | 1987-09-23 | — | — | EP | disclosed |
| US-4454158-A | Allyl amine MAO inhibitors | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-06-12 | — | — | US | disclosed |
| EP-0067105-A2 | Allyl amine MAO inhibitors | MERRELL DOW FRANCE ET CIE (FR) | 1982-12-15 | — | — | EP | disclosed |