Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 8/20 | 0.58 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | NMBR | P28336 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722758 | 1.00 | REN (0.58) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10722764 | 1.00 | REN (0.58) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10722609 | 1.00 | REN (0.58) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10724545 | 1.00 | REN (0.58) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10720899 | 0.97 | REN (0.56) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10720894 | 0.97 | REN (0.56) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10724746 | 0.92 | REN (0.56) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10725374 | 0.92 | REN (0.56) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10720813 | 0.92 | REN (0.56) | RENCTSBCTSKCASP3CTSD | |
| SCHEMBL10720804 | 0.92 | REN (0.56) | RENCTSBCTSKCASP3CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |