Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.46 |
| ▸ | CTSG | P08311 | 4/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.46 |
| ▸ | CMA1 | P23946 | 4/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877218 | 0.88 | POLB (0.58) | POLBCYP3A4CYP2C9 | |
| SCHEMBL10718302 | 0.85 | POLB (0.51) | POLBMEN1KMT2ANPC1CYP3A4 | |
| SCHEMBL9825783 | 0.83 | POLB (0.52) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9714102 | 0.80 | POLB (0.76) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9714106 | 0.80 | POLB (0.76) | POLBCYP3A4CYP2C9 | |
| SCHEMBL10719018 | 0.76 | POLB (0.47) | POLBCYP3A4CYP2C9 | |
| SCHEMBL9824746 | 0.75 | POLB (0.46) | POLBMEN1KMT2ANPC1CYP3A4 | |
| SCHEMBL9825688 | 0.74 | POLB (0.53) | POLBKMT2ACYP3A4CYP2C9 | |
| SCHEMBL9876990 | 0.74 | POLB (0.53) | POLBKMT2ACYP3A4CYP2C9 | |
| SCHEMBL8177791 | 0.74 | POLB (0.56) | POLBKMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |