Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9877218 | 0.86 | POLB (0.58) | POLBCYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL9824746 | 0.86 | POLB (0.46) | POLBCYP3A4CYP2C9ALDH1A1HPGD | |
| SCHEMBL9825708 | 0.82 | ALDH1A1 (0.46) | POLBKDM4EALDH1A1HPGD | |
| SCHEMBL9825783 | 0.81 | POLB (0.52) | POLBCYP3A4CYP2C9ALDH1A1LMNA | |
| SCHEMBL10718302 | 0.80 | POLB (0.51) | POLBCYP3A4CYP2C9KDM4EALDH1A1 | |
| SCHEMBL10718578 | 0.80 | ABCB1 (0.45) | LMNA | |
| SCHEMBL10718541 | 0.78 | POLB (0.72) | POLBCYP3A4CYP2C9 | |
| SCHEMBL10722631 | 0.76 | POLB (0.47) | POLBCYP3A4CYP2C9 | |
| SCHEMBL10721420 | 0.76 | LMNA (0.44) | ALDH1A1LMNA | |
| SCHEMBL9877608 | 0.73 | MEN1 (0.43) | ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236618-A2 | Insecticidal N'-substituted-N,N'-diacylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |