Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 19/20 | 0.58 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10722766 | 1.00 | REN (0.58) | RENCTSD | |
| SCHEMBL11015169 | 0.94 | REN (0.60) | REN | |
| SCHEMBL11015387 | 0.94 | REN (0.60) | REN | |
| SCHEMBL11014872 | 0.94 | REN (0.60) | REN | |
| SCHEMBL10722982 | 0.94 | REN (0.62) | REN | |
| SCHEMBL10722990 | 0.94 | REN (0.62) | REN | |
| SCHEMBL10721187 | 0.94 | REN (0.60) | REN | |
| SCHEMBL10721178 | 0.94 | REN (0.60) | REN | |
| SCHEMBL10722914 | 0.92 | REN (0.62) | REN | |
| SCHEMBL10722910 | 0.92 | REN (0.62) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |