SCHEMBL10723213

SCHEMBL10723213

CCCCCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NC(C)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 5/20 0.69
SMN1; SMN2 Q16637 1/20 0.61
SLC6A5 Q9Y345 1/20 0.61
MEN1 O00255 1/20 0.58
MAPK1 P28482 1/20 0.58
KMT2A Q03164 1/20 0.58
NOD1 Q9Y239 3/20 0.51
PLA2G10 O15496 2/20 0.48
PLA2G2C Q5R387 1/20 0.47
DNM1 Q05193 1/20 0.47
ALDH1A1 P00352 2/20 0.46
MAPT P10636 1/20 0.46
ASAH1 Q13510 1/20 0.46
ACER2 Q5QJU3 1/20 0.46
MME P08473 1/20 0.45
ACE P12821 1/20 0.45
CPA1 P15085 1/20 0.45
ACE2 Q9BYF1 1/20 0.45
HSP90AA1 P07900 1/20 0.44
PLA2G2A P14555 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27689822 1.00 FAAH (0.69) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL21585637 1.00 FAAH (0.69) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL10723219 1.00 FAAH (0.69) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL21585636 1.00 FAAH (0.69) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL23203158 0.98 FAAH (0.72) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL20503297 0.98 FAAH (0.72) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL21585630 0.98 FAAH (0.72) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL23203547 0.98 FAAH (0.72) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL21585629 0.98 FAAH (0.72) FAAHSMN1; SMN2SLC6A5MEN1MAPK1
SCHEMBL10723781 0.98 FAAH (0.72) FAAHSMN1; SMN2SLC6A5MEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4665053-A HYDROPHOBIC CARBOXYLIC MODIFIER CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 1987-05-12 US disclosed