Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.33 |
| ▸ | CDC42BPB | Q9Y5S2 | 4/20 | 0.33 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10721669 | 0.76 | CSNK1A1 (0.39) | CSNK1A1TYRO3DYRK1BADRA1AHCRTR1 | |
| SCHEMBL10723167 | 0.76 | CSNK1A1 (0.39) | CSNK1A1TYRO3DYRK1BADRA1AHCRTR1 | |
| SCHEMBL9113864 | 0.73 | CSNK1A1 (0.43) | CSNK1A1TYRO3DYRK1BADRA1AHRH3 | |
| SCHEMBL9395846 | 0.71 | BCHE (0.49) | KMT2A | |
| SCHEMBL28000729 | 0.71 | ALDH1A1 (0.46) | CSNK1A1TYRO3DYRK1BADRA1AKCNH2 | |
| SCHEMBL9695392 | 0.70 | DRD4 (0.44) | — | |
| SCHEMBL8617533 | 0.69 | CSNK1A1 (0.44) | CSNK1A1TYRO3DYRK1BADRA1AHCRTR1 | |
| SCHEMBL8537274 | 0.68 | CSNK1A1 (0.46) | CSNK1A1TYRO3DYRK1BADRA1AHCRTR1 | |
| SCHEMBL10717715 | 0.64 | NPY5R (0.38) | DYRK1BNPBWR1KMT2A | |
| SCHEMBL10479892 | 0.64 | CSNK1A1 (0.34) | CSNK1A1TYRO3DYRK1BHCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0248634-A2 | Stabilized benzimidazole derivative and composition | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-12-09 | — | — | EP | disclosed |