Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.30 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.30 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727769 | 0.88 | PTPN1 (0.33) | PTPN1IDH1ABCB1UGT1A1DPP4 | |
| SCHEMBL10723585 | 0.82 | CYP3A4 (0.34) | ABCB1 | |
| SCHEMBL316065 | 0.76 | POLB (0.35) | KMT2A | |
| SCHEMBL10354213 | 0.76 | CYP3A4 (0.40) | — | |
| SCHEMBL1348416 | 0.74 | KMT2A (0.33) | KMT2A | |
| SCHEMBL9850337 | 0.71 | MAPK1 (0.33) | PTPN1KMT2A | |
| SCHEMBL122561 | 0.70 | POLB (0.38) | KMT2A | |
| SCHEMBL363479 | 0.68 | MAPT (0.41) | KMT2A | |
| SCHEMBL382358 | 0.68 | GLRA3 (0.36) | — | |
| SCHEMBL1716755 | 0.68 | GLRA3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4705888-A | POLYMERIZATION CATALYSTS | AKZO NV (NL) | 1987-11-10 | — | — | US | disclosed |