Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.75 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | PKLR | P30613 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GPR183 | P32249 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | NSD2 | O96028 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11977000 | 0.93 | ATM (0.70) | MCOLN3POLBALDH1A1KMT2ALMNA | |
| SCHEMBL104325 | 0.92 | MCOLN3 (0.71) | MCOLN3POLBALDH1A1KMT2APKM | |
| SCHEMBL25613354 | 0.92 | MCOLN3 (0.71) | MCOLN3POLBALDH1A1KMT2APKM | |
| SCHEMBL25442196 | 0.91 | LMNA (0.73) | MCOLN3POLBALDH1A1KMT2APKM | |
| SCHEMBL12049590 | 0.91 | USP2 (0.71) | MCOLN3POLBKMT2ALMNAMEN1 | |
| SCHEMBL4555390 | 0.91 | USP2 (0.71) | MCOLN3POLBKMT2ALMNAMEN1 | |
| SCHEMBL12656155 | 0.89 | KMT2A (0.70) | MCOLN3POLBALDH1A1KMT2APKM | |
| SCHEMBL14923984 | 0.88 | POLB (0.64) | MCOLN3POLBALDH1A1KMT2APKM | |
| SCHEMBL9976064 | 0.88 | MAPT (0.68) | MCOLN3POLBALDH1A1KMT2APKM | |
| SCHEMBL12015807 | 0.88 | POLB (0.67) | MCOLN3POLBALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |