Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CTSG | P08311 | 1/20 | 0.54 |
| ▸ | CMA1 | P23946 | 1/20 | 0.54 |
| ▸ | GBA1 | P04062 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7130175 | 0.91 | POLB (0.61) | CHRM4FAAHKMT2APOLBLMNA | |
| SCHEMBL2954361 | 0.91 | POLB (0.67) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31684034 | 0.90 | TSHR (0.78) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4555453 | 0.90 | TSHR (0.78) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2961026 | 0.89 | CHRM4 (0.62) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27974780 | 0.88 | CHRM4 (0.54) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5247397 | 0.88 | KMT2A (0.59) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL2962429 | 0.88 | MEN1 (0.62) | CHRM4KMT2AMEN1CTSGCMA1 | |
| SCHEMBL3223553 | 0.88 | CHRM4 (0.61) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3247291 | 0.87 | CNR1 (0.56) | CHRM4TSHRCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663641-A | LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |