Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10727381 | 1.00 | KCNH2 (0.44) | KCNH2KDM4EALDH1A1GAASREBF2 | |
| SCHEMBL10726956 | 1.00 | KCNH2 (0.44) | KCNH2KDM4EALDH1A1GAASREBF2 | |
| SCHEMBL10726656 | 0.98 | KCNH2 (0.41) | KCNH2KDM4EALDH1A1GAASREBF2 | |
| SCHEMBL10726673 | 0.94 | SREBF2 (0.41) | KCNH2KDM4EALDH1A1GAASREBF2 | |
| SCHEMBL10723303 | 0.88 | SREBF2 (0.49) | KCNH2KDM4EALDH1A1SREBF2CYP2E1 | |
| SCHEMBL10160879 | 0.81 | CYP2C9 (0.46) | KCNH2KDM4EALDH1A1SREBF2CYP2E1 | |
| SCHEMBL15071803 | 0.78 | LTA4H (0.56) | KDM4EALDH1A1GAACYP3A4LTA4H | |
| SCHEMBL1102349 | 0.78 | LTA4H (0.56) | KDM4EALDH1A1GAACYP3A4LTA4H | |
| SCHEMBL6417507 | 0.78 | LTA4H (0.56) | KDM4EALDH1A1GAACYP3A4LTA4H | |
| SCHEMBL10723207 | 0.77 | GRIN1 (0.40) | KCNH2KDM4EALDH1A1SREBF2CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659503-A | Pyridylthiophenes | Merck Patent Gesellschaft Mit Beschrankter Huftung (DE) | 1987-04-21 | — | — | US | disclosed |