SCHEMBL10724802

SCHEMBL10724802

CC[C@H](C)[C@@H](CO)NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10724797 1.00 REN (0.61) REN
SCHEMBL10720636 0.97 REN (0.59) REN
SCHEMBL10720645 0.97 REN (0.59) REN
SCHEMBL10723611 0.97 REN (0.58) REN
SCHEMBL10723566 0.97 REN (0.58) REN
SCHEMBL10723605 0.97 REN (0.58) REN
SCHEMBL10723572 0.97 REN (0.58) REN
SCHEMBL10725433 0.96 REN (0.57) REN
SCHEMBL10725437 0.96 REN (0.57) REN
SCHEMBL10721291 0.94 REN (0.55) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4698329-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-06 — — US disclosed
EP-0152255-A2 New renin-inhibitory peptides and their use SANKYO COMPANY LIMITED (JP) 1985-08-21 — — EP disclosed
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