Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724362 | 0.95 | REN (0.60) | RENCTSBCTSK | |
| SCHEMBL10724857 | 0.95 | REN (0.60) | RENCASP3CTSBCTSKCTSD | |
| SCHEMBL10720136 | 0.95 | REN (0.60) | RENCTSBCTSK | |
| SCHEMBL10720805 | 0.95 | REN (0.60) | RENCTSBCTSK | |
| SCHEMBL10720794 | 0.95 | REN (0.60) | RENCTSBCTSK | |
| SCHEMBL10720131 | 0.95 | REN (0.60) | RENCTSBCTSK | |
| SCHEMBL11016025 | 0.94 | REN (0.61) | RENCTSBCTSKCTSD | |
| SCHEMBL11016020 | 0.94 | REN (0.61) | RENCTSBCTSKCTSD | |
| SCHEMBL10721231 | 0.94 | REN (0.62) | RENCASP3CTSBCTSKCTSD | |
| SCHEMBL10721238 | 0.94 | REN (0.62) | RENCASP3CTSBCTSKCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4698329-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-06 | — | — | US | disclosed |