SCHEMBL10726344

SCHEMBL10726344

C=C(N)NCc1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 3/20 0.56
ALDH1A1 P00352 2/20 0.56
HPGD P15428 1/20 0.56
GRIN2D O15399 2/20 0.55
GRIN3B O60391 2/20 0.55
GRIN1 Q05586 2/20 0.55
GRIN2A Q12879 2/20 0.55
GRIN2B Q13224 2/20 0.55
GRIN2C Q14957 2/20 0.55
GRIN3A Q8TCU5 2/20 0.55
SIGMAR1 Q99720 2/20 0.55
GAA P10253 3/20 0.54
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
POLB P06746 1/20 0.54
CA12 O43570 2/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA9 Q16790 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11206259 0.98 ALOX12 (0.54) ALOX12ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL8711125 0.84 ALOX12 (0.59) ALOX12ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL3343137 0.81 ALOX12 (0.67) ALOX12ALDH1A1HPGDGAAMAPT
SCHEMBL14065008 0.81 ALOX12 (0.60) ALOX12ALDH1A1HPGDGAAMAPT
SCHEMBL11665803 0.79 CYP2D6 (0.55) ALOX12ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL10731587 0.78 NPC1 (0.59) ALDH1A1HPGDGAAMAPTCA12
SCHEMBL24347533 0.78 ALOX12 (0.52) ALOX12ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL14620410 0.78 CYP1A2 (0.53) ALOX12ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL16935670 0.77 ALOX12 (0.56) ALOX12ALDH1A1HPGDGRIN2DGRIN3B
SCHEMBL81511 0.77 CYP2C19 (0.64) ALOX12ALDH1A1HPGDGRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4655970-A ONE STEP CIBA-GEIGY AG (CH) 1987-04-07 US claimed
US-4393007-A ONE STEP PRODUCTION OF ANTHRAQUINONE DYES FROM 1-NITRO-ANTHRAQUINONE CIBA-GEIGY AG (CH) 1983-07-12 US claimed
US-4655970-A ONE STEP CIBA-GEIGY AG (CH) 1987-04-07 US disclosed
US-4393007-A ONE STEP PRODUCTION OF ANTHRAQUINONE DYES FROM 1-NITRO-ANTHRAQUINONE CIBA-GEIGY AG (CH) 1983-07-12 US disclosed