Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 3/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.40 |
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728359 | 1.00 | FAAH (0.53) | FAAHSLC6A5SMN1; SMN2APLNRACE | |
| SCHEMBL10728822 | 1.00 | FAAH (0.53) | FAAHSLC6A5SMN1; SMN2APLNRACE | |
| SCHEMBL10728411 | 0.92 | FAAH (0.46) | FAAHSLC6A5SMN1; SMN2APLNRACE | |
| SCHEMBL10728408 | 0.92 | FAAH (0.46) | FAAHSLC6A5SMN1; SMN2APLNRACE | |
| SCHEMBL10728862 | 0.91 | FAAH (0.49) | FAAHSLC6A5SMN1; SMN2ACEACE2 | |
| SCHEMBL10728795 | 0.91 | FAAH (0.49) | FAAHSLC6A5SMN1; SMN2ACEACE2 | |
| SCHEMBL10728801 | 0.91 | FAAH (0.49) | FAAHSLC6A5SMN1; SMN2ACEACE2 | |
| SCHEMBL10726064 | 0.90 | FAAH (0.43) | FAAHSLC6A5SMN1; SMN2APLNRACE | |
| SCHEMBL10723247 | 0.90 | CNR2 (0.47) | FAAHSLC6A5SMN1; SMN2APLNRLPAR3 | |
| SCHEMBL10723217 | 0.90 | FAAH (0.43) | FAAHSLC6A5SMN1; SMN2APLNRACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665053-A | HYDROPHOBIC CARBOXYLIC MODIFIER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1987-05-12 | — | — | US | claimed |
| EP-0126009-B1 | PEPTIDE DERIVATIVES, THEIR PREPARATION AND USE AS ELASTASE INHIBITORS | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1987-01-14 | — | — | EP | claimed |
| EP-0126009-A1 | Peptide derivatives, their preparation and use as elastase inhibitors | Etablissement Public dit: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 1984-11-21 | — | — | EP | claimed |
| US-4665053-A | HYDROPHOBIC CARBOXYLIC MODIFIER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1987-05-12 | — | — | US | disclosed |