Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 12/20 | 0.68 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10726116 | 0.90 | ADORA2A (0.68) | ADORA2AADORA2BADORA3ADORA1KDM4E | |
| SCHEMBL10728449 | 0.90 | ADORA2A (0.68) | ADORA2AADORA2BADORA3ADORA1KDM4E | |
| SCHEMBL10726169 | 0.89 | ADORA2A (0.67) | ADORA2AADORA2BADORA3ADORA1KDM4E | |
| SCHEMBL10728405 | 0.89 | ADORA2A (0.71) | ADORA2AADORA2BADORA3ADORA1KDM4E | |
| SCHEMBL10729007 | 0.88 | ADORA2B (0.69) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10723411 | 0.86 | ADORA2A (0.67) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10723870 | 0.85 | ADORA2A (0.81) | ADORA2AADORA2BADORA3ADORA1KDM4E | |
| SCHEMBL10723882 | 0.85 | ADORA2A (0.80) | ADORA2AADORA2BADORA3ADORA1KDM4E | |
| SCHEMBL10728457 | 0.84 | ADORA2A (0.64) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL10723397 | 0.84 | ADORA2A (0.62) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4696932-A | ANTIALLERGENS, ANTIHISTAMINES, CARDIOTONIC AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1987-09-29 | — | — | US | claimed |