Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.54 |
| ▸ | DRD1 | P21728 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.54 |
| ▸ | DRD3 | P35462 | 3/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734779 | 0.86 | DRD3 (0.69) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10734785 | 0.86 | DRD1 (0.54) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10733897 | 0.85 | KDM1A (0.41) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10729400 | 0.84 | DRD3 (0.55) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11574284 | 0.83 | SETD7 (0.76) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10728200 | 0.81 | DRD1 (0.51) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| Citatepine SCHEMBL2112235 | 0.80 | DRD2 (0.51) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL10733612 | 0.79 | DRD3 (0.47) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11092794 | 0.79 | CYP3A4 (0.52) | CHRM2HTR1AADRA2ACHRM1DRD1 | |
| SCHEMBL11115502 | 0.78 | CYP3A4 (0.48) | CHRM2HTR1AADRA2ACHRM1DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707476-A | TRANQUILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |