Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9377603 | 0.93 | HTT (0.42) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL7949242 | 0.92 | HTT (0.45) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL28354766 | 0.91 | HTT (0.49) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL9239878 | 0.91 | HTT (0.49) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL1100395 | 0.89 | HTT (0.54) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL21986292 | 0.89 | HTT (0.54) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL7949239 | 0.88 | HTT (0.47) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL5073201 | 0.88 | HTT (0.46) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL7950342 | 0.87 | HTT (0.48) | HTTMAPTMAPK1APAF1THRB | |
| SCHEMBL28058769 | 0.85 | HTT (0.41) | HTTMAPTMAPK1APAF1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4661545-A | PHOSPHITE ADDITIVES FOR STYRENE-MALEIC ANHYDRIDE COPOLYMERS; ANTISTICKING, DECOMPOSITION PREVENTION | STAMICARBON B.V. (LICENSING SUBSIDIARY OF DSM) (NL) | 1987-04-28 | — | — | US | disclosed |
| EP-0183313-A1 | Thermoplastic moulding compound | STAMICARBON B.V. (NL) | 1986-06-04 | — | — | EP | disclosed |