⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4450628 | 0.94 | THRB (0.36) | — | |
| Ammonia Solution, Strong SCHEMBL17709159 | 0.94 | THRB (0.36) | — | |
| Ammonia Solution, Strong SCHEMBL4601834 | 0.94 | THRB (0.36) | — | |
| SCHEMBL5547 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL3965533 | 0.88 | — | — | |
| SCHEMBL7156637 | 0.88 | THRB (0.39) | — | |
| Hydrochloric Acid SCHEMBL4079466 | 0.88 | — | — | |
| SCHEMBL31990 | 0.88 | — | — | |
| SCHEMBL20472787 | 0.88 | THRB (0.39) | — | |
| Hydrochloric Acid SCHEMBL28763342 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113856483-A | High-boron-removal polyamide reverse osmosis membrane and preparation method thereof | 万华化学集团股份有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-107429189-B | Lubricant composition | NOK克鲁伯有限公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-107429189-A | Lubricant composition | NOK克鲁伯有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107406792-A | grease composition | NOK克鲁伯有限公司 | 2017-11-28 | — | — | CN | disclosed |
| US-20160367542-A1 | NICOTINAMIDE DERIVATE IN THE TREATMENT OF ACUTE CORONARY SYNDROME | GLAXOSMITHKLINE LLC (US) | 2016-12-22 | — | — | US | disclosed |
| US-20150209337-A1 | NICOTINAMIDE DERIVATE IN THE TREATMENT OF ACUTE CORONARY SYNDROME | GLAXOSMITHKLINE LLC | 2015-07-30 | — | — | US | disclosed |
| EP-2874627-A1 | NICOTINAMIDE DERIVATE IN THE TREATMENT OF ACUTE CORONARY SYNDROME | Glaxosmithkline LLC (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014014706-A1 | NICOTINAMIDE DERIVATE IN THE TREATMENT OF ACUTE CORONARY SYNDROME | GLAXOSMITHKLINE LLC (US) | 2014-01-23 | — | — | WO | disclosed |
| EP-2274295-A1 | 3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | Merck Frosst Canada Ltd. (CA) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009135299-A1 | 3, 4 - SUBSTITUTED PIPERIDINE DERIVATIVES AS RENIN INHIBITORS | MERCK FROSST CANADA LTD. (CA) | 2009-11-12 | — | — | WO | disclosed |
| EP-0434213-B1 | Monosubstituted dithiooxamide compounds and their use | MINNESOTA MINING & MFG (US) | 1995-04-05 | — | — | EP | disclosed |
| US-5124308-A | Reacts with transition metal salt for carbonless paper copying | MINNESOTA MINING AND MANUFACTURING COMPANY | 1992-06-23 | — | — | US | disclosed |
| US-5041654-A | Transamination in wallach reaction; controlling temperature; reactant amine concentration | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0434213-A1 | Monosubstituted dithiooxamide compounds and their use | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| EP-0431783-A1 | Preparation of monosubstituted dithiooxamide compounds | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-06-12 | — | — | EP | disclosed |