Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.39 |
| ▸ | DRD4 | P21917 | 6/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.39 |
| ▸ | HRH1 | P35367 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | HRH2 | P25021 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10728860 | 0.85 | MAPK1 (0.41) | MAPK1CYP1A2CYP2D6TDP1MAPT | |
| SCHEMBL10952178 | 0.83 | AHR (0.50) | MAPK1AHRDRD2TDP1HRH1 | |
| SCHEMBL10729951 | 0.81 | MAPK1 (0.50) | MAPK1AHRDRD2DRD4CYP1A2 | |
| SCHEMBL10730117 | 0.81 | MAPK1 (0.49) | MAPK1AHRDRD2DRD4CYP1A2 | |
| SCHEMBL19537683 | 0.76 | MAPK1 (0.57) | MAPK1AHRDRD2DRD4CYP1A2 | |
| SCHEMBL10734569 | 0.72 | CYP3A4 (0.46) | MAPK1DRD2DRD4CYP1A2CYP3A4 | |
| SCHEMBL10733451 | 0.72 | MAPK1 (0.44) | MAPK1CYP1A2CYP3A4CYP2D6HRH4 | |
| SCHEMBL11266316 | 0.71 | MAPK1 (0.53) | MAPK1AHRDRD2DRD4CYP1A2 | |
| SCHEMBL10732001 | 0.70 | MAPK1 (0.42) | MAPK1DRD2DRD4CYP1A2CYP3A4 | |
| SCHEMBL8170350 | 0.70 | MAPK1 (0.48) | MAPK1AHRDRD2DRD4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707476-A | TRANQUILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |