Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.38 |
| ▸ | HRH2 | P25021 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD5 | P21918 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732142 | 0.88 | KDM4E (0.35) | MAPK1HRH4DRD3CYP1A2CYP2D6 | |
| SCHEMBL10956290 | 0.85 | AHR (0.40) | MAPK1DRD2HRH1ADRA2AADRA2C | |
| SCHEMBL10733698 | 0.78 | DRD2 (0.44) | MAPK1DRD2DRD4HRH4HRH1 | |
| SCHEMBL10729951 | 0.76 | MAPK1 (0.50) | MAPK1DRD2DRD4HRH4HRH2 | |
| SCHEMBL11574884 | 0.74 | SETD7 (0.47) | MAPK1DRD2DRD4HRH4HRH2 | |
| SCHEMBL10730117 | 0.72 | MAPK1 (0.49) | MAPK1DRD2DRD4HRH4HRH2 | |
| SCHEMBL10733451 | 0.72 | MAPK1 (0.44) | MAPK1HRH4CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL10731007 | 0.70 | MAPK1 (0.47) | MAPK1DRD2DRD4HRH4HRH2 | |
| SCHEMBL10734681 | 0.69 | ACVR1 (0.39) | CHRM1CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL10729429 | 0.68 | KDM4E (0.35) | CHRM2HTR1AADRA2AADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4707476-A | TRANQUILIZERS | CIBA-GEIGY CORPORATION (US) | 1987-11-17 | — | — | US | disclosed |