Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655952 | 0.91 | DPP4 (0.50) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL10653881 | 0.90 | DPP4 (0.48) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL11276787 | 0.90 | LMNA (0.51) | KDM4ELMNAHSD17B10OPRK1KMT2A | |
| SCHEMBL10653563 | 0.86 | KMT2A (0.54) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL10731089 | 0.83 | DPP4 (0.48) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL11047766 | 0.82 | LMNA (0.50) | DPP4CHRM2DRD1KDM4ELMNA | |
| SCHEMBL10654645 | 0.82 | DPP4 (0.58) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL9437310 | 0.81 | DPP4 (0.50) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL10656681 | 0.81 | DPP4 (0.56) | DPP4CHRM2DRD1KDM4EABCC4 | |
| SCHEMBL8133502 | 0.80 | DPP4 (0.47) | DPP4CHRM2DRD1KDM4EABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649144-A | Antibacterial 7-(3-amino-1-pyrrolidinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1987-03-10 | — | — | US | disclosed |