Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17997163 | 0.84 | ALDH1A1 (0.60) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL14288405 | 0.83 | ALDH1A1 (0.56) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL8827913 | 0.80 | ALDH1A1 (0.70) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL11749330 | 0.79 | ALDH1A1 (0.77) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL10670216 | 0.78 | RECQL (0.48) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL5962424 | 0.77 | ALDH1A1 (0.66) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL8827915 | 0.77 | POLB (0.74) | ALDH1A1POLBMEN1KMT2AMAPT | |
| SCHEMBL10478322 | 0.76 | ALDH1A1 (0.54) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL11742390 | 0.76 | ALDH1A1 (0.65) | ALDH1A1POLBMEN1KMT2ATP53 | |
| SCHEMBL2373723 | 0.75 | ALDH1A1 (0.60) | ALDH1A1POLBMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4663323-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4540703-A | Tetrazole derivatives, anti-ulcer composition containing the same and method for treating ulcers | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |
| EP-0035046-A1 | Novel tetrazole derivatives, process for the preparation thereof, and anti-ulcer composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-09-09 | — | — | EP | disclosed |