Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.34 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.34 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732025 | 0.91 | HPGD (0.38) | HPGDCYP1A2CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL10899959 | 0.84 | KMT2A (0.41) | HPGDCNR1ALDH1A1L3MBTL1TDP1 | |
| SCHEMBL10733838 | 0.82 | KMT2A (0.38) | HPGDALDH1A1L3MBTL1TDP1ALOX15 | |
| SCHEMBL10736180 | 0.82 | L3MBTL1 (0.40) | CNR1ALDH1A1L3MBTL1TDP1ALOX15 | |
| SCHEMBL10948933 | 0.82 | KMT2A (0.37) | HPGDALDH1A1TDP1EPHX2NPSR1 | |
| SCHEMBL10735404 | 0.82 | POLM (0.41) | HPGDALDH1A1L3MBTL1TDP1ALOX15 | |
| SCHEMBL10950579 | 0.81 | HPGD (0.41) | HPGDALDH1A1L3MBTL1TDP1ALOX15 | |
| SCHEMBL10944971 | 0.81 | HPGD (0.38) | HPGDALDH1A1TDP1ALOX15NPSR1 | |
| SCHEMBL10948656 | 0.79 | HPGD (0.39) | HPGDALDH1A1ALOX15GAANPSR1 | |
| SCHEMBL10951881 | 0.78 | KMT2A (0.40) | CYP1A2CYP2C19ALDH1A1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4659372-A | MITICIDE, MITE OVICIDE, AND HERBICIDES | UNION CARBIDE CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| US-4613617-A | Synergistic insecticidal compositions containing dione esters | UNION CARBIDE CORPORATION (US) | 1986-09-23 | — | — | US | disclosed |
| US-4422870-A | MITICIDE, MITE OVICIDE, HERBICIDE | UNION CARBIDE CORPORATION (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0007243-B1 | 2-ARYL-1,3-CYCLOHEXANEDIONE COMPOUNDS AND ALKALI METAL SALTS, AMMONIUM SALTS AND ENOL ESTERS THEREOF, COMPOSITION AND METHOD OF CONTROLLING ACARINA ECTOPARASITES ON WARMBLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1982-11-17 | — | — | EP | disclosed |
| US-4175135-A | Method of controlling acarina ectoparasites on warmblooded animals by orally administering to the animal an ectoparasitically effective amount of a 2-aryl-1,3-cyclohexanedione compound, and alkali metal salts, ammonium salts and enol esters thereof | UNION CARBIDE CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |