Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 5/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10660755 | 0.79 | GPBAR1 (0.40) | GPBAR1PTGS1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL11557039 | 0.76 | PTGS1 (0.43) | GPBAR1PTGS1SMN1; SMN2ALDH1A1HTR7 | |
| SCHEMBL10664107 | 0.75 | STK17B (0.40) | GPBAR1PTGS1SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL10657153 | 0.74 | HIF1A (0.42) | GPBAR1PTGS1ALDH1A1PKMKMT2A | |
| SCHEMBL10659627 | 0.73 | PTGS1 (0.41) | GPBAR1PTGS1SMN1; SMN2ALDH1A1HTR7 | |
| SCHEMBL10728658 | 0.72 | PLAU (0.36) | GPBAR1PTGS1HTR7DPP4ADORA2A | |
| SCHEMBL10510443 | 0.71 | PTGS1 (0.37) | GPBAR1PTGS1LMNAALDH1A1HTR7 | |
| SCHEMBL10734711 | 0.71 | PTGS1 (0.35) | GPBAR1PTGS1HTR7MAPK1MAPT | |
| SCHEMBL11562701 | 0.71 | PTGS1 (0.42) | GPBAR1PTGS1SMN1; SMN2ALDH1A1HTR7 | |
| SCHEMBL10658344 | 0.71 | PTGS1 (0.42) | GPBAR1PTGS1SMN1; SMN2LMNAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | claimed |