SCHEMBL1073374

SCHEMBL1073374

Cl[Sn](Cl)(Cl)Oc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.45
TSHR P16473 2/20 0.45
CA4 P22748 1/20 0.41
KCNA3 P22001 1/20 0.38
CA5A P35218 1/20 0.36
CA5B Q9Y2D0 1/20 0.36
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
MAOA P21397 1/20 0.35
TAAR1 Q96RJ0 1/20 0.33
ALDH1A1 P00352 1/20 0.33
RECQL P46063 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
SRC P12931 1/20 0.33
ORAI1 Q96D31 1/20 0.33
ORAI2 Q96SN7 1/20 0.33
ORAI3 Q9BRQ5 1/20 0.33
TRPV6 Q9H1D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1072988 0.82 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL1074226 0.82 LTA4H (0.45) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL151768 0.75 LTA4H (0.50) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL8463963 0.69 LTA4H (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL2698710 0.67 CA4 (0.43) LTA4HTSHRCA4KCNA3CA5A
SCHEMBL28674478 0.65
SCHEMBL226327 0.65
SCHEMBL3098534 0.65
SCHEMBL11028002 0.65
SCHEMBL14905 0.63 LTA4H (0.60) LTA4HTSHRCA4KCNA3CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2271681-B1 METHODS OF PREPARING A POLYMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL CO (US) 2013-10-23 EP claimed
US-8211988-B2 Methods of preparing a polymerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-03 US claimed
EP-2271681-A1 METHODS OF PREPARING A POLYMERIZATION CATALYST Chevron Phillips Chemical Company LP (US) 2011-01-12 EP claimed
WO-2009134361-A1 METHODS OF PREPARING A POLYMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-11-05 WO claimed
US-20090275710-A1 Methods of preparing a polymerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP 2009-11-05 US claimed
EP-2271681-B1 METHODS OF PREPARING A POLYMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL CO (US) 2013-10-23 EP disclosed
US-8211988-B2 Methods of preparing a polymerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-03 US disclosed
EP-2271681-A1 METHODS OF PREPARING A POLYMERIZATION CATALYST Chevron Phillips Chemical Company LP (US) 2011-01-12 EP disclosed
WO-2009134361-A1 METHODS OF PREPARING A POLYMERIZATION CATALYST CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2009-11-05 WO disclosed
US-20090275710-A1 Methods of preparing a polymerization catalyst CHEVRON PHILLIPS CHEMICAL COMPANY LP 2009-11-05 US disclosed
EP-0107857-A1 Process for the preparation of 8,12-epoxy-13,14,15,16-tetranor labdane Consortium für elektrochemische Industrie GmbH (DE) 1984-05-09 EP disclosed