Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.92 |
| ▸ | HTT | P42858 | 1/20 | 0.92 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | F3 | P13726 | 1/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MGAM | O43451 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | SI | P14410 | 3/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MIF | P14174 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL979654 | 1.00 | ALDH1A1 (0.92) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL979655 | 1.00 | ALDH1A1 (0.92) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL9047295 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL11807335 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL9047298 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL11807333 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL10959168 | 0.98 | ALDH1A1 (0.89) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL812295 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL1524525 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HTTCYP1A2F3AKR1C3 | |
| SCHEMBL809531 | 0.96 | ALDH1A1 (1.00) | ALDH1A1HTTCYP1A2F3AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117701516-A | Alkene reductase, enzyme preparation, nucleic acid, expression vector, preparation method and application | 河北工业大学 | 2024-03-15 | — | — | CN | disclosed |
| CN-112972441-B | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2022-08-23 | — | — | CN | disclosed |
| CN-112972441-A | Application of monocarbonyl curcumin compound in preparation of medicine for preventing and treating periodontitis | 温州医科大学附属口腔医院 | 2021-06-18 | — | — | CN | disclosed |
| CN-109111334-B | Chiral 2-arylmethylene cycloalkanol and asymmetric synthesis method thereof | 三峡大学 | 2020-07-28 | — | — | CN | disclosed |
| CN-106861757-B | A kind of organic boron of fluorescent marker/nitrogen lewis acid base bifunctional catalyst and preparation method thereof | 湖南大学 | 2019-08-09 | — | — | CN | disclosed |
| CN-109111334-A | A kind of chirality 2- aryl methylene cyclic alkanol and its method of asymmetric synthesis | 三峡大学 | 2019-01-01 | — | — | CN | disclosed |
| US-7872029-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | BOWEN J PHILLIP | 2011-01-18 | — | — | US | disclosed |
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Robinson, Thomas Philip (US) | 2009-01-15 | — | — | US | disclosed |
| US-7432303-B2 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | Bowen, J. Phillip (US) | 2008-10-07 | — | — | US | disclosed |
| EP-1322590-B1 | 5-AMINO-1-PENTENE-3-OL SUBSTITUTED DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-05-02 | — | — | EP | disclosed |
| US-4652559-A | ANALGESIC, ANTIDEPRESSANT | THE UPJOHN COMPANY (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0085811-B1 | 2-(PHENYLMETHYLENE)CYCLOALKYLAMINES | THE UPJOHN COMPANY (US) | 1986-05-07 | — | — | EP | disclosed |
| US-4540690-A | ANALGESICS, ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0085811-A1 | 2-(Phenylmethylene)cycloalkylamines | THE UPJOHN COMPANY (US) | 1983-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018167-A1 | Chalcone and its analogs as agents for the inhibition of angiogenesis and related disease states | FLT1, FLT4, VEGFA | ALDH1A1 1941/4885HTT 469/4885CYP1A2 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.