Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10732187 | 0.92 | MEN1 (0.48) | MRGPRX4MEN1KMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL10735781 | 0.91 | MRGPRX4 (0.45) | MRGPRX4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10732909 | 0.87 | ALDH1A1 (0.44) | MRGPRX4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11412285 | 0.83 | TSHR (0.42) | MEN1KMT2AALDH1A1MCL1 | |
| SCHEMBL10907005 | 0.82 | NPC1 (0.46) | MRGPRX4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7171205 | 0.81 | S1PR4 (0.40) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10905808 | 0.81 | MRGPRX4 (0.42) | MRGPRX4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10905417 | 0.81 | MRGPRX4 (0.44) | MRGPRX4MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL10734513 | 0.80 | CLCN2 (0.47) | MRGPRX4SMN1; SMN2BACE1MCL1 | |
| Hydrochloric Acid SCHEMBL10907709 | 0.80 | MRGPRX4 (0.44) | MRGPRX4MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4704401-A | HYPOTENSIVE AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1987-11-03 | — | — | US | disclosed |
| US-4487779-A | HYPOTENSIVE AGENTS | WILLIAM H. RORER, INC. (US) | 1984-12-11 | — | — | US | disclosed |