SCHEMBL10734860

SCHEMBL10734860

CC(C)=CCCC(C)=CCCC(C)=CCCC(C)C(C#N)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FNTA P49354 9/20 0.56
FNTB P49356 9/20 0.56
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
TRPA1 O75762 1/20 0.46
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10730874 1.00 FNTA (0.56) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL10730865 1.00 FNTA (0.56) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL10734851 1.00 FNTA (0.56) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL11244966 0.84 FNTA (0.44) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL11244964 0.84 FNTA (0.44) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL1532213 0.78 FNTA (0.45) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL10000168 0.78 FNTA (0.66) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL10000156 0.76 FNTA (0.63) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL30707741 0.73 FNTA (0.74) FNTAFNTBKMT2AMAPTMEN1
SCHEMBL16792146 0.73 FNTA (1.00) FNTAFNTBKMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4639450-A LIVER DISORDERS EISAI CO., LTD. (JP) 1987-01-27 US disclosed
EP-0098620-B1 ALPHA,BETA-DIHYDROPOLYPRENYL DERIVATIVES AND A PROCESS FOR PREPARING THESE DERIVATIVES Eisai Co., Ltd. (JP) 1986-09-17 EP disclosed
US-4456603-A Polyprenylcarboxylic acid amides useful for treating liver dysfunction EISAI CO., LTD. (JP) 1984-06-26 US disclosed
EP-0098620-A2 Alpha,beta-dihydropolyprenyl derivatives and a process for preparing these derivatives Eisai Co., Ltd. (JP) 1984-01-18 EP disclosed