Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 8/20 | 1.00 |
| ▸ | FNTB | P49356 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | SQLE | Q14534 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11703920 | 1.00 | FNTA (1.00) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL8625937 | 0.98 | FNTA (0.96) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL8625931 | 0.98 | FNTA (0.96) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL9129708 | 0.98 | FNTA (0.96) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL17223965 | 0.93 | FNTA (0.86) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL17223966 | 0.93 | FNTA (0.86) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL3271383 | 0.91 | FNTA (0.83) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL11549345 | 0.89 | FNTA (0.79) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL11551176 | 0.89 | FNTA (0.79) | FNTAFNTBKMT2AKDM4EATM | |
| SCHEMBL11549341 | 0.89 | FNTA (0.79) | FNTAFNTBKMT2AKDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015089349-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015084721-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-11 | — | — | WO | disclosed |