Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | PNKP | Q96T60 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10731961 | 0.91 | PPARG (0.39) | PPARGCCNE1CDK2 | |
| SCHEMBL10737994 | 0.85 | PPARG (0.35) | PPARGPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL28236280 | 0.81 | PPARG (0.36) | PPARGPRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL10731938 | 0.77 | PPARG (0.37) | PPARGCCNE1CDK2 | |
| SCHEMBL10346358 | 0.76 | ALDH1A1 (0.44) | — | |
| SCHEMBL29629330 | 0.74 | PPARG (0.40) | PPARG | |
| SCHEMBL28596564 | 0.74 | PPARG (0.40) | PPARG | |
| SCHEMBL28596563 | 0.74 | PPARG (0.40) | PPARG | |
| SCHEMBL28230084 | 0.74 | PPARG (0.38) | PPARGPRKCD | |
| SCHEMBL3113825 | 0.73 | GRM2 (0.39) | PPARGPRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4650812-A | ANTIALLERGY | HOFFMANN-LA ROCHE INC. (US) | 1987-03-17 | — | — | US | disclosed |