⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466457 | 0.77 | ALDH1A1 (0.35) | — | |
| SCHEMBL19705374 | 0.74 | — | — | |
| SCHEMBL2774770 | 0.72 | — | — | |
| SCHEMBL14762066 | 0.70 | ALDH1A1 (0.43) | — | |
| SCHEMBL28629077 | 0.67 | ALDH1A1 (0.44) | — | |
| SCHEMBL6965759 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL11528652 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL11413136 | 0.65 | ALDH1A1 (0.41) | — | |
| SCHEMBL9640 | 0.65 | — | — | |
| SCHEMBL21765845 | 0.65 | ALDH1A1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448946-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | Novartis AG (CH) | 2012-05-09 | — | — | EP | disclosed |
| WO-2011000855-A1 | 2-CARBOXAMIDE CYCLOAMINO UREAS USEFUL AS PI3K INHIBITORS | NOVARTIS AG (CH) | 2011-01-06 | — | — | WO | disclosed |
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5661159-A | TREATING OR PREVENTING ALLERGY OR INFLAMMATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0626956-B1 | QUINOLYLBENZOFURAN DERIVATIVES AS LEUKOTRIENE ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |