Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438911 | 0.84 | SMN1; SMN2 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7431045 | 0.83 | SMN1; SMN2 (0.47) | HSD17B10SMN1; SMN2LMNA | |
| SCHEMBL10743623 | 0.81 | SMN1; SMN2 (0.52) | HTTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL6827646 | 0.80 | HTT (0.59) | HTTTGM2FOLH1KEAP1NFE2L2 | |
| SCHEMBL7423509 | 0.80 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2LMNA | |
| SCHEMBL9738061 | 0.80 | FOLH1 (0.60) | TGM2FOLH1MMP3SIRT2SIRT1 | |
| SCHEMBL9738069 | 0.80 | FOLH1 (0.60) | TGM2FOLH1MMP3SIRT2SIRT1 | |
| SCHEMBL6823763 | 0.79 | FOLH1 (0.58) | HTTTGM2FOLH1KEAP1NFE2L2 | |
| SCHEMBL11758185 | 0.79 | HTT (0.58) | HTTTGM2FOLH1KEAP1NFE2L2 | |
| Hydrochloric Acid SCHEMBL10739661 | 0.79 | SMN1; SMN2 (0.54) | HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4665087-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |