Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.60 |
| ▸ | MMP2 | P08253 | 3/20 | 0.57 |
| ▸ | MMP9 | P14780 | 3/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.54 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.54 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | TGM2 | P21980 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738069 | 1.00 | FOLH1 (0.60) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL11023043 | 0.88 | FOLH1 (0.58) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL11024671 | 0.88 | FOLH1 (0.58) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL9738257 | 0.88 | FOLH1 (0.61) | FOLH1MMP2MMP9SIRT2CPB1 | |
| SCHEMBL9738268 | 0.88 | FOLH1 (0.61) | FOLH1MMP2MMP9SIRT2CPB1 | |
| SCHEMBL12433264 | 0.88 | CTSK (0.51) | FOLH1MMP9MMP1MMP3ACE | |
| SCHEMBL4426973 | 0.88 | CTSK (0.51) | FOLH1MMP9MMP1MMP3ACE | |
| SCHEMBL9810164 | 0.85 | FOLH1 (0.53) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL9810168 | 0.85 | FOLH1 (0.53) | FOLH1MMP2MMP9SIRT2SIRT1 | |
| SCHEMBL9856603 | 0.85 | SIRT2 (0.52) | FOLH1MMP2MMP9SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151432-A | Cognition activators to improve memory, inhibitors of angiotensin converting enzymes, cardiovascular disorders and learning dysfunction | ADIR ET COMPAGNIE (FR) | 1992-09-29 | — | — | US | disclosed |