Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.43 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.43 |
| ▸ | ABAT | P80404 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6015468 | 0.82 | ALDH1A1 (0.38) | KMT2AALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9129337 | 0.81 | KMT2A (0.40) | KMT2ACYP2A6ALDH5A1ABATALDH1A1 | |
| SCHEMBL8397324 | 0.81 | ALDH1A1 (0.48) | KMT2AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL17748388 | 0.81 | HSD17B10 (0.35) | KMT2AALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL1755559 | 0.81 | KMT2A (0.49) | KMT2ACYP2A6ALDH5A1ABATALDH1A1 | |
| SCHEMBL10816139 | 0.81 | ALDH1A1 (0.45) | KMT2ACYP2A6ALDH5A1ABATALDH1A1 | |
| SCHEMBL10550388 | 0.79 | KMT2A (0.44) | KMT2ACYP2A6ALDH5A1ABATALDH1A1 | |
| SCHEMBL9129340 | 0.78 | KMT2A (0.42) | KMT2ACYP2A6ALDH5A1ABATALDH1A1 | |
| SCHEMBL19591200 | 0.77 | KMT2A (0.40) | KMT2ACYP2A6ALDH5A1ABATALDH1A1 | |
| SCHEMBL9246634 | 0.77 | KMT2A (0.37) | KMT2ACYP2A6ALDH5A1ABATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582903-A | Synthesis of unsaturated hydantoins with an inexpensive catalyst | STAUFFER CHEMICAL COMPANY (US) | 1986-04-15 | — | — | US | claimed |
| US-4345072-A | Process for the production of 5-arylidene hydantoins (B) | DEGUSSA AG (DE) | 1982-08-17 | — | — | US | claimed |
| US-7851658-B2 | Palladium-catalyzed carbon-carbon bond forming reactions | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-14 | — | — | US | disclosed |
| US-4684735-A | Promotion of raney nickel hydrogenation catalyst | STAUFFER CHEMICAL COMPANY (US) | 1987-08-04 | — | — | US | disclosed |
| US-4650876-A | INCREMENTAL ADDITION TO PREVENT FOAMING, RANEY CATALYST | STAUFFER CHEMICAL COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| EP-0210683-A1 | Promotion of raney nickel catalyst | STAUFFER CHEMICAL COMPANY (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4613691-A | Preparation of amino acids from unsaturated hydantoins | STAUFFER CHEMICAL COMPANY (US) | 1986-09-23 | — | — | US | disclosed |
| US-4582903-A | Synthesis of unsaturated hydantoins with an inexpensive catalyst | STAUFFER CHEMICAL COMPANY (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0177072-A2 | Preparation of amino acids from unsaturated hydantoins | STAUFFER CHEMICAL COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |
| US-4345072-A | Process for the production of 5-arylidene hydantoins (B) | DEGUSSA AG (DE) | 1982-08-17 | — | — | US | disclosed |