Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP4C | P60510 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737730 | 1.00 | PPP4C (0.66) | PPP4CMAPTTDP1MEN1JAK2 | |
| SCHEMBL10734714 | 0.91 | PPP4C (0.67) | PPP4CMAPTTDP1 | |
| SCHEMBL10734710 | 0.91 | PPP4C (0.67) | PPP4CMAPTTDP1 | |
| SCHEMBL469218 | 0.88 | PPP4C (0.84) | PPP4CMAPTTDP1MEN1JAK2 | |
| SCHEMBL10734734 | 0.82 | PPP4C (0.55) | PPP4CMAPTTDP1MEN1JAK2 | |
| SCHEMBL10734738 | 0.82 | PPP4C (0.55) | PPP4CMAPTTDP1MEN1JAK2 | |
| Fostriecin SCHEMBL469219 | 0.79 | PPP4C (1.00) | PPP4CMAPTTDP1MEN1JAK2 | |
| Fostriecin SCHEMBL10738892 | 0.79 | PPP4C (1.00) | PPP4CMAPTTDP1MEN1JAK2 | |
| Fostriecin SCHEMBL62527 | 0.79 | PPP4C (1.00) | PPP4CMAPTTDP1MEN1JAK2 | |
| Fostriecin SCHEMBL10738899 | 0.79 | PPP4C (1.00) | PPP4CMAPTTDP1MEN1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0128651-A2 | Pyranones and related compounds and methods for their production and use | WARNER-LAMBERT COMPANY (US) | 1984-12-19 | — | — | EP | claimed |
| US-4680416-A | Antibiotic CL-1565 complex derivatives | WARNER-LAMBERT COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0128651-A2 | Pyranones and related compounds and methods for their production and use | WARNER-LAMBERT COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |