Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.84 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | HPGD | P15428 | 4/20 | 0.78 |
| ▸ | HTT | P42858 | 4/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | BRD4 | O60885 | 1/20 | 0.78 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | MEN1 | O00255 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.66 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.66 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pefloxacin SCHEMBL28251251 | 0.91 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL7824014 | 0.91 | DRD3 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL34292 | 0.91 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL29351730 | 0.91 | DRD3 (1.00) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL11022977 | 0.91 | DRD3 (0.83) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL10911017 | 0.90 | DRD3 (0.98) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL9788090 | 0.90 | DRD3 (0.98) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL22698592 | 0.90 | HSD17B10 (0.84) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL8184732 | 0.90 | DRD3 (0.98) | DRD3HSD17B10KDM4EALDH1A1HPGD | |
| Pefloxacin SCHEMBL9800276 | 0.90 | DRD3 (0.98) | DRD3HSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62174055-A | — | — | None | — | — | JP | disclosed |
| WO-2015095227-A2 | PEPTIDOMIMETIC COMPOUNDS AND ANTIBODY-DRUG CONJUGATES THEREOF | GENENTECH, INC. (US) | 2015-06-25 | — | — | WO | disclosed |
| US-4686221-A | Quinolinecarboxylic acid compounds and antimicrobial agent containing the same | KANEBO, LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| JP-S62174055-A | NOVEL QUINOLINECARBOXYLIC ACID DERIVATIVE AND ANTI-BACTERIAL AGENT CONTAINING SAME AS ACTIVE INGREDIENT | KANEBO LTD | 1987-07-30 | — | — | JP | disclosed |
| EP-0220523-A2 | Novel quinolinecarboxylic acid compounds, processes for preparing them, pharmaceutical composition and use | KANEBO, LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |