Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10734952 | 0.82 | BCHE (0.41) | BCHEACHE | |
| SCHEMBL10737316 | 0.79 | TERT (0.32) | — | |
| SCHEMBL10735988 | 0.78 | SLC47A1 (0.55) | — | |
| SCHEMBL10741417 | 0.77 | SLC47A1 (0.38) | — | |
| SCHEMBL10733534 | 0.77 | SLC47A1 (0.38) | — | |
| SCHEMBL10737226 | 0.75 | SLC47A1 (0.34) | BCHEACHE | |
| SCHEMBL10734457 | 0.75 | SLC47A1 (0.38) | BCHEACHE | |
| SCHEMBL10737576 | 0.75 | SLC47A1 (0.34) | BCHEACHE | |
| SCHEMBL10741729 | 0.74 | KMT2A (0.36) | BCHEACHE | |
| SCHEMBL10739507 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4656176-A | 2-thiazolyl, oxazolyl, triazolyl and thiadiazolyl alkylamino-3-nitro-heterocyclic compounds | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1987-04-07 | — | — | US | disclosed |
| US-4525477-A | HISTAMINE H2-ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1985-06-25 | — | — | US | disclosed |
| US-4405624-A | ANTIHISTAMINES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-09-20 | — | — | US | disclosed |
| EP-0005984-B1 | NITRO COMPOUNDS, PROCESSES FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1983-06-22 | — | — | EP | disclosed |
| US-4324789-A | 1-Benzyl-5-nitro-4-(pyridyl or imidazolyl) alkylamino-1,2,3,6-tetrahydropyrimidines and blocking of histamine H2 | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1982-04-13 | — | — | US | disclosed |
| US-4238493-A | HISTAMINE H2-RECEPTOR ANTAGONISTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1980-12-09 | — | — | US | disclosed |
| EP-0005984-A1 | Nitro compounds, processes for preparing them and compositions containing them | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1979-12-12 | — | — | EP | disclosed |