Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | KLK7 | P49862 | 8/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639437 | 0.79 | RAB9A (0.50) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL7555674 | 0.76 | POLB (0.61) | MEN1KMT2AMAPTALDH1A1RXFP1 | |
| SCHEMBL11713690 | 0.75 | MAPT (0.48) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL10740441 | 0.75 | TSHR (0.59) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL11511231 | 0.74 | KLK7 (0.44) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL18456226 | 0.73 | MME (0.63) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL4151615 | 0.73 | MME (0.63) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL5550287 | 0.73 | MEN1 (0.67) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL12205972 | 0.73 | MME (0.63) | MEN1KMT2AKLK7MAPTALDH1A1 | |
| SCHEMBL11452160 | 0.73 | CYP1A2 (0.64) | MEN1KMT2AMAPTALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4636508-A | 5-pyrimidinecarboxyamides and treatment of leukemia therewith | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-01-13 | — | — | US | disclosed |