Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740476 | 1.00 | PPARA (0.57) | PPARAPLA2G4BALBLTB4RLTB4R2 | |
| SCHEMBL8080152 | 0.93 | PPARA (0.61) | PPARAPLA2G4BALBLTB4RLTB4R2 | |
| SCHEMBL8080149 | 0.93 | PPARA (0.61) | PPARAPLA2G4BALBLTB4RLTB4R2 | |
| SCHEMBL8087469 | 0.91 | PPARA (0.62) | PPARAPLA2G4BALBLTB4RLTB4R2 | |
| SCHEMBL8087464 | 0.91 | PPARA (0.62) | PPARAPLA2G4BALBLTB4RLTB4R2 | |
| SCHEMBL8080020 | 0.89 | PPARA (0.59) | PPARAALBLTB4RLTB4R2PPARG | |
| SCHEMBL8080022 | 0.89 | PPARA (0.59) | PPARAALBLTB4RLTB4R2PPARG | |
| SCHEMBL10739398 | 0.87 | MGLL (0.50) | PPARAMAPTHSD17B10ALOX15PGR | |
| SCHEMBL10739403 | 0.87 | MGLL (0.50) | PPARAMAPTHSD17B10ALOX15PGR | |
| SCHEMBL13464287 | 0.86 | NR5A1 (0.54) | PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4713486-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. (GB) | 1987-12-15 | — | — | US | disclosed |
| EP-0109225-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | disclosed |
| EP-0109225-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-05-23 | — | — | EP | disclosed |