Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.60 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.50 |
| ▸ | HMGCR | P04035 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944019 | 1.00 | FFAR1 (0.60) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 | |
| SCHEMBL11109365 | 0.86 | CYP3A4 (0.64) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 | |
| SCHEMBL10795247 | 0.86 | CYSLTR2 (0.65) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 | |
| SCHEMBL10745835 | 0.86 | CYP3A4 (0.52) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 | |
| SCHEMBL10753710 | 0.81 | CYP3A4 (0.55) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 | |
| SCHEMBL10799919 | 0.81 | CYP3A4 (0.48) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 | |
| SCHEMBL21149881 | 0.80 | CYP3A4 (0.54) | CYSLTR2CYSLTR1TDP1KDM4ELMNA | |
| SCHEMBL10744806 | 0.78 | CYSLTR2 (0.57) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 | |
| SCHEMBL10435206 | 0.78 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1 | |
| SCHEMBL10743657 | 0.77 | CYP3A4 (0.60) | FFAR1CYSLTR2CYSLTR1FFAR4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109225-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | claimed |
| EP-0109225-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-05-23 | — | — | EP | claimed |
| US-4713486-A | ANTIALLERGENS | BEECHAM GROUP P.L.C. (GB) | 1987-12-15 | — | — | US | disclosed |
| EP-0109225-B1 | ARACHIDONIC ACID ANALOGUES, PROCESSES FOR THEIR PREPARATION AND THEIR USE IN MEDICINE | BEECHAM GROUP PLC (GB) | 1985-08-28 | — | — | EP | disclosed |
| EP-0109225-A1 | Arachidonic acid analogues, processes for their preparation and their use in medicine | BEECHAM GROUP PLC (GB) | 1984-05-23 | — | — | EP | disclosed |