Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.65 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.61 |
| ▸ | HMGCR | P04035 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 2/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP12 | P39900 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10740872 | 0.86 | FFAR1 (0.60) | CYSLTR2CYSLTR1PTPN7HMGCRTDP1 | |
| SCHEMBL4944019 | 0.86 | FFAR1 (0.60) | CYSLTR2CYSLTR1PTPN7HMGCRTDP1 | |
| SCHEMBL10744806 | 0.85 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PTPN7HMGCRTDP1 | |
| SCHEMBL6371432 | 0.85 | KCNH2 (0.58) | CYSLTR2CYSLTR1TDP1FFAR1FFAR4 | |
| SCHEMBL10794849 | 0.84 | CYP3A4 (0.55) | CYSLTR2CYSLTR1PTPN7TDP1RECQL | |
| SCHEMBL10795643 | 0.82 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PTPN7HMGCRTDP1 | |
| SCHEMBL11109365 | 0.82 | CYP3A4 (0.64) | CYSLTR2CYSLTR1PTPN7HMGCRTDP1 | |
| SCHEMBL10795652 | 0.82 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PTPN7HMGCRTDP1 | |
| SCHEMBL10795660 | 0.82 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PTPN7HMGCRTDP1 | |
| SCHEMBL28453497 | 0.81 | FFAR1 (0.55) | CYSLTR2CYSLTR1PTPN7TDP1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | claimed |
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |