SCHEMBL1074384

SCHEMBL1074384

O=CCc1ccccc1C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 2/20 0.55
ALDH1A1 P00352 5/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.50
KDM4E B2RXH2 2/20 0.45
HMGB1 P09429 2/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
HPGD P15428 1/20 0.45
CA4 P22748 1/20 0.45
CA6 P23280 1/20 0.45
CA7 P43166 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
CA9 Q16790 1/20 0.45
NAPRT Q6XQN6 1/20 0.45
CA14 Q9ULX7 1/20 0.45
TP53 P04637 1/20 0.45
HTT P42858 1/20 0.45
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11897168 0.85 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRKDM4E
SCHEMBL11897138 0.85 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRKDM4E
SCHEMBL11897139 0.85 FOLH1 (0.57) FOLH1ALDH1A1ALOX15TSHRKDM4E
Benzene SCHEMBL27083018 0.83 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRKDM4E
SCHEMBL89060 0.83 FOLH1 (0.55) FOLH1ALDH1A1ALOX15TSHRKDM4E
SCHEMBL29930782 0.83 TDP1 (0.46) FOLH1ALDH1A1TSHRKDM4ETP53
SCHEMBL29008092 0.82 HMGB1 (0.42) FOLH1ALDH1A1ALOX15TSHRKDM4E
SCHEMBL10447451 0.82 FOLH1 (0.45) FOLH1ALDH1A1ALOX15TSHRKDM4E
SCHEMBL8930563 0.82 KDM4E (0.47) ALDH1A1TSHRKDM4EHPGDGAA
SCHEMBL11094883 0.82 FOLH1 (0.53) FOLH1ALDH1A1ALOX15TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025085560-A1 LYSINE ACETYLTRANSFERASE INHIBITORS Kronos Bio, Inc. (US) 2025-04-24 WO disclosed
WO-2025085564-A1 LYSINE ACETYLTRANSFERASE INHIBITORS Kronos Bio, Inc. (US) 2025-04-24 WO disclosed
CN-119431272-A Preparation method of (S) -3-methyl- (2-piperidylphenyl) -1-butylamine acetyl glutamate 北京斯利安药业有限公司 2025-02-14 CN disclosed
CN-113325098-B Synchronous analysis and detection method for micro-plastics and organic pollutants in soil 浙江省计量科学研究院 2022-11-08 CN disclosed
CN-110467558-B Reaction method for synthesizing 3-aminoisoindolinone under catalysis of nickel 山东省科学院新材料研究所 2022-09-16 CN disclosed
CN-114423740-A Pyrazole derivatives for controlling arthropods 拜耳动物保健有限责任公司 2022-04-29 CN disclosed
CN-109456324-B Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them 法国施维雅药厂 2022-04-22 CN disclosed
CN-113325098-A Synchronous analysis and detection method for micro-plastic and organic pollutants in soil 浙江省计量科学研究院 2021-08-31 CN disclosed
EP-2505576-B1 CYCLIC COMPOUND, PROCESS FOR PRODUCTION THEREOF, RADIATION-SENSITIVE COMPOSITION, AND RESIST PATTERN FORMATION METHOD MITSUBISHI GAS CHEMICAL CO (JP) 2019-04-24 EP disclosed
US-8969629-B2 Cyclic compound, production process thereof, radiation-sensitive composition and resist pattern formation method MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2015-03-03 US disclosed
WO-1999036409-A1 METABOLICALLY INERT ANTI-INFLAMMATORY AND ANTI-TUMOR ANTIFOLATES NAIR MADHAVAN G (US) 1999-07-22 WO disclosed
US-5895820-A OXIDATION OF DIALKYL AROMATIC ALDEHYDE AND/OR CARBOXYLIC ACIDIN PRESENCE OF HEAVY METAL CATALYST AND BROMINE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-04-20 US disclosed
EP-0896960-A2 Process for the production of trimellitic acid and process for the production of trimellitic acid anhydride MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1999-02-17 EP disclosed
CN-1142497-A Naphthalene derivatives, process for preparation thereof, and intermediates therefor TANABE SEIYAKU CO (JP) 1997-02-12 CN disclosed
EP-0161939-B1 ARYLHYDROXAMATES E.R. Squibb & Sons, Inc. (US) 1993-07-21 EP disclosed
EP-0240859-B1 LIPOXYGENASE INHIBITING COMPOUNDS ABBOTT LABORATORIES (US) 1993-04-28 EP disclosed
US-4761403-A QUINOLONE DERIVATIVES ABBOTT LABORATORIES (US) 1988-08-02 US disclosed
EP-0240859-A2 Lipoxygenase inhibiting compounds ABBOTT LABORATORIES (US) 1987-10-14 EP disclosed
US-4607053-A L2POXYGENASE INHIBITORS E. R. SQUIBB & SONS, INC. (US) 1986-08-19 US disclosed
EP-0161939-A2 Arylhydroxamates E.R. Squibb & Sons, Inc. (US) 1985-11-21 EP disclosed