SCHEMBL10447451

SCHEMBL10447451

O=CCc1cccc(C(=O)O)c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 3/20 0.45
HMGB1 P09429 2/20 0.42
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 1/20 0.41
MMP2 P08253 1/20 0.40
CLCN2 P51788 1/20 0.39
TSHR P16473 2/20 0.39
AKR1C3 P42330 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
DUSP3 P51452 1/20 0.38
PTPN5 P54829 1/20 0.38
PTPN11 Q06124 1/20 0.38
CTDSP1 Q9GZU7 1/20 0.38
GAA P10253 1/20 0.37
KDM4E B2RXH2 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1137942 0.84 GABRA1 (0.46) FOLH1HMGB1ALDH1A1ALOX15CLCN2
SCHEMBL2731264 0.84 MRGPRX4 (0.46) FOLH1HMGB1ALDH1A1ALOX15MMP2
SCHEMBL1074384 0.82 FOLH1 (0.55) FOLH1HMGB1ALDH1A1ALOX15CLCN2
SCHEMBL29008092 0.81 HMGB1 (0.42) FOLH1HMGB1ALDH1A1ALOX15MMP2
SCHEMBL10877484 0.81 XPO1 (0.43) FOLH1HMGB1MMP2CLCN2TSHR
SCHEMBL31090800 0.80 FOLH1 (0.50) FOLH1HMGB1ALDH1A1ALOX15CLCN2
SCHEMBL23708 0.80 FOLH1 (0.50) FOLH1HMGB1ALDH1A1ALOX15CLCN2
SCHEMBL22912 0.80 FOLH1 (0.59) FOLH1HMGB1ALDH1A1ALOX15CLCN2
SCHEMBL29367715 0.80 FOLH1 (0.50) FOLH1HMGB1ALDH1A1ALOX15CLCN2
SCHEMBL7565345 0.80 G6PD (0.52) FOLH1HMGB1ALDH1A1ALOX15MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023121292-A1 POLYMER COMPOUND AND APPLICATION THEREOF 주식회사 삼양사 2023-06-29 WO claimed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP claimed
WO-2023121292-A1 POLYMER COMPOUND AND APPLICATION THEREOF 주식회사 삼양사 2023-06-29 WO disclosed
EP-0399755-A1 Light-sensitive composition and presensitized plate for use in making lithographic printing plates Fuji Photo Film Co., Ltd. (JP) 1990-11-28 EP disclosed