Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP10 | Q14694 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GALR2 | O43603 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10741826 | 0.85 | USP10 (0.39) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL17977297 | 0.81 | USP10 (0.58) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL7017708 | 0.80 | USP10 (0.57) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL10747018 | 0.80 | USP47 (0.52) | USP10MAPT | |
| SCHEMBL3878737 | 0.79 | USP10 (0.56) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL28786633 | 0.79 | USP10 (0.56) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL1455300 | 0.79 | USP10 (0.56) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL3881580 | 0.76 | USP10 (0.53) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL32685857 | 0.73 | LMNA (0.57) | USP10ALDH1A1LMNAPOLBNPSR1 | |
| SCHEMBL9050509 | 0.72 | USP10 (0.49) | USP10ALDH1A1LMNAPOLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4649154-A | AGRICULTURE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1987-03-10 | — | — | US | disclosed |
| US-4451660-A | AGRICULTURE, HORTICULTURE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1984-05-29 | — | — | US | disclosed |
| EP-0031173-B1 | NEW NITROTHIOPHENES, METHOD OF PREPARING THE NEW COMPOUNDS, AS WELL AS FUNGICIDAL AND/OR BACTERICIDAL COMPOSITIONS ON THE BASIS OF THE NEW COMPOUNDS | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1983-09-14 | — | — | EP | disclosed |
| EP-0031173-A1 | New nitrothiophenes, method of preparing the new compounds, as well as fungicidal and/or bactericidal compositions on the basis of the new compounds | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1981-07-01 | — | — | EP | disclosed |