Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6050607 | 0.73 | ALDH1A1 (0.35) | KMT2A | |
| SCHEMBL11580726 | 0.72 | KMT2A (0.42) | KMT2A | |
| SCHEMBL10746141 | 0.71 | — | — | |
| SCHEMBL9792805 | 0.69 | KDM4E (0.50) | — | |
| SCHEMBL14788233 | 0.69 | ALDH1A1 (0.32) | — | |
| SCHEMBL20631048 | 0.68 | PTGDR2 (0.37) | — | |
| SCHEMBL11398605 | 0.66 | PCSK9 (0.38) | — | |
| SCHEMBL7313158 | 0.66 | NTRK1 (0.43) | KMT2A | |
| SCHEMBL20673878 | 0.66 | BRD4 (0.49) | KMT2A | |
| SCHEMBL11388287 | 0.65 | GSK3B (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4710506-A | Antihypertensive thienopyridines | THE BOOTS COMPANY PLC (GB) | 1987-12-01 | — | — | US | disclosed |
| EP-0209977-A2 | Thienopyridones, processes and intermediates for their preparation and pharmaceutical compositions containing them | The Boots Company PLC (GB) | 1987-01-28 | — | — | EP | disclosed |