Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPRA | P18433 | 1/20 | 0.53 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745859 | 0.94 | TSHR (0.62) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10741167 | 0.91 | ALDH1A1 (0.61) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL4156603 | 0.89 | ATM (0.65) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL4156601 | 0.89 | ATM (0.65) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10347067 | 0.89 | ALDH1A1 (0.58) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10915929 | 0.89 | ALDH1A1 (0.58) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10868030 | 0.89 | ALDH1A1 (0.58) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10791119 | 0.88 | ALDH1A1 (0.64) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10744547 | 0.88 | ALDH1A1 (0.67) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 | |
| SCHEMBL10868472 | 0.88 | BIRC2 (0.57) | ALDH1A1THRBCYP2C9CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668625-A | Process for preparing peptides | FARMITALIA CARLO ERBA (IT) | 1987-05-26 | — | — | US | claimed |
| US-4668625-A | Process for preparing peptides | FARMITALIA CARLO ERBA (IT) | 1987-05-26 | — | — | US | disclosed |