Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17A | Q9UEE5 | 5/20 | 0.40 |
| ▸ | FERMT2 | Q96AC1 | 2/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9220618 | 0.80 | STK17A (0.44) | STK17ASTK17BMAPT | |
| Hydrochloric Acid SCHEMBL25431317 | 0.79 | STK17A (0.40) | STK17AFERMT2CHEK1STK17BP4HTM | |
| SCHEMBL31587661 | 0.76 | FERMT2 (0.36) | STK17AFERMT2CHEK1HDAC1MAPT | |
| SCHEMBL4574251 | 0.76 | KMT2A (0.53) | HDAC1MAPT | |
| SCHEMBL31587480 | 0.75 | FERMT2 (0.33) | STK17AFERMT2CHEK1HDAC1LCK | |
| SCHEMBL17315402 | 0.73 | PTK2 (0.39) | STK17AFERMT2CHEK1P4HTMZAP70 | |
| SCHEMBL3005414 | 0.73 | TAAR1 (0.46) | STK17AFERMT2STK17BMAPTCDK1 | |
| SCHEMBL17315227 | 0.72 | PTK2 (0.53) | MAPT | |
| Hydrochloric Acid SCHEMBL3027696 | 0.71 | TAAR1 (0.44) | STK17AFERMT2STK17BMAPTCDK1 | |
| SCHEMBL22957175 | 0.71 | LOXL2 (0.43) | STK17AFERMT2CHEK1ROCK1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140377750-A1 | Methods and Systems for Detecting Nucleic Acids | APPLIED BIOSYSTEMS, LLC (US) | 2014-12-25 | — | — | US | disclosed |
| US-20140045716-A1 | Methods and Systems for Detecting Nucleic Acids | APPLIED BIOSYSTEMS, LLC (US) | 2014-02-13 | — | — | US | disclosed |
| US-20130164748-A1 | Detection of nucleic acid amplification | APPLIED BIOSYSTEMS LLC (US) | 2013-06-27 | — | — | US | disclosed |
| EP-2118310-B1 | SYSTEMS AND METHODS FOR DETECTING NUCLEIC ACIDS | APPLIED BIOSYSTEMS LLC (US) | 2013-03-06 | — | — | EP | disclosed |
| US-20110014617-A1 | Methods and Systems for Detecting Nucleic Acids | Life Technologies Corporation (US) | 2011-01-20 | — | — | US | disclosed |
| EP-2118310-A1 | SYSTEMS AND METHODS FOR DETECTING NUCLEIC ACIDS | Applied Biosystems, LLC (US) | 2009-11-18 | — | — | EP | disclosed |
| EP-2069525-A1 | SYSTEMS AND METHODS FOR DETECTING NUCLEIC ACIDS | Applied Biosystems, LLC (US) | 2009-06-17 | — | — | EP | disclosed |
| US-20080318248-A1 | Compositions and Methods of Screening Apoproteins | VIAMET PHARMACEUTICALS, INC (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080241838-A1 | METHODS AND SYSTEMS FOR DETECTING NUCLEIC ACIDS | APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) | 2008-10-02 | — | — | US | disclosed |
| US-20080193940-A1 | SYSTEMS AND METHODS FOR DETECTING NUCLEIC ACIDS | APPLERA CORPORATION, APPLIED BIOSYSTEMS GROUP (US) | 2008-08-14 | — | — | US | disclosed |
| EP-1193315-A1 | Microelectronic device for electrochemical detection | University of North Carolina at Chapel Hill et al. (US) | 2002-04-03 | — | — | EP | disclosed |
| US-20020037530-A1 | Detection of binding reactions using labels detected by mediated catalytic electrochemistry | STEWART DAVID H (US) | 2002-03-28 | — | — | US | disclosed |
| EP-1185692-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | The University of North Carolina at Chapel Hill (US) | 2002-03-13 | — | — | EP | disclosed |
| US-6346387-B1 | CONTACTING IMMOBILIZED BINDER WITH TEST SAMPLE TO COMPLEX TARGET; CONTACTING WITH SECOND BINDER HAVING EXOGENOUS OR ENDOGENOUS LABEL; OXIDATION WITH TRANSITION METAL COMPOUND; DETECTING OXIDATION-REDUCTION REACTION | XANTHON, INC. | 2002-02-12 | — | — | US | disclosed |
| WO-2000065099-A1 | MONOLAYER AND ELECTRODE FOR DETECTING A LABEL-BEARING TARGET AND METHOD OF USE THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-11-02 | — | — | WO | disclosed |
| US-6132971-A | APPARATUS FOR ELECTROCHEMICAL DETECTION OF A BINDING PAIR; FOR THE EFFICIENT AND ACCURATE DETECTION OF MUTATIONS IN NUCLEOTIDE SEQUENCES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-10-17 | — | — | US | disclosed |
| US-6127127-A | Monolayer and electrode for detecting a label-bearing target and method of use thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-10-03 | — | — | US | disclosed |
| US-5968745-A | ELECTRODE OF SUBSTRATE HAVING ELECTROCONDUCTIVE WORKING SURFACE AND A NONCONDUCTIVE OUTER POLYMER LAYER WHERE PROBES CAN BE ATTACHED HAVING MICROFLUIDIC REACTION OPENINGS FOR TRANSITION METAL COMPLEX TO TRANSFER ELECTRONS TO SURFACE | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-10-19 | — | — | US | disclosed |
| US-5871918-A | DNA AND RNA HYBRIDIZATION DETECTION BY REACTION WITH TRANSITION METAL COMPLEX FOR OXIDATION-REDUCTION REACTION | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-02-16 | — | — | US | disclosed |
| US-5171853-A | Process of cleaving nucleic acids with oxoruthenium(IV) complexes | NORTH CAROLINA STATE UNIVERSITY (US) | 1992-12-15 | — | — | US | disclosed |