Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 12/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 13/20 | 0.45 |
| ▸ | SIRT3 | Q9NTG7 | 4/20 | 0.45 |
| ▸ | SIRT5 | Q9NXA8 | 4/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1587596 | 0.95 | SIRT1 (0.51) | SIRT1SIRT2SIRT3SIRT5 | |
| SCHEMBL9488093 | 0.95 | SIRT1 (0.51) | SIRT1SIRT2SIRT3SIRT5 | |
| SCHEMBL4301229 | 0.88 | PTGER4 (0.44) | SIRT1SIRT5PTGER4 | |
| SCHEMBL9489620 | 0.88 | SIRT2 (0.44) | SIRT1SIRT2SIRT3SIRT5 | |
| SCHEMBL9489607 | 0.88 | SIRT2 (0.44) | SIRT1SIRT2SIRT3SIRT5 | |
| SCHEMBL9614367 | 0.86 | NPY4R (0.42) | — | |
| SCHEMBL6696292 | 0.83 | PTGER4 (0.46) | SIRT1SIRT2SIRT3SIRT5PTGER4 | |
| SCHEMBL28595330 | 0.82 | KDM4E (0.38) | SIRT1SIRT2 | |
| SCHEMBL28595326 | 0.82 | KDM4E (0.38) | SIRT1SIRT2 | |
| SCHEMBL29985699 | 0.82 | SIRT1 (0.54) | SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2276776-B1 | METHOD AND AFFINITY COLUMN FOR PURIFYING PROTEINS | SAMSUNG ELECTRONICS CO LTD (KR) | 2015-07-29 | — | — | EP | disclosed |
| EP-2276776-A2 | METHOD AND AFFINITY COLUMN FOR PURIFYING PROTEINS | Samsung Electronics Co., Ltd. (KR) | 2011-01-26 | — | — | EP | disclosed |
| WO-2009139601-A2 | METHOD AND AFFINITY COLUMN FOR PURIFYING PROTEINS | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2009-11-19 | — | — | WO | disclosed |