Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.40 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.40 |
| ▸ | CDK2 | P24941 | 2/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 6/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.39 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.39 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | POLG | P54098 | 1/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502621 | 0.83 | ENPP1 (0.52) | P2RY1ENPP1P2RX1P2RX3P2RY2 | |
| SCHEMBL1071388 | 0.82 | CDK1 (0.36) | CDK1CCNB1CCNE1CDK2P2RY1 | |
| SCHEMBL1035726 | 0.81 | ENPP1 (0.51) | P2RY1ENPP1P2RX1P2RX3P2RY2 | |
| SCHEMBL8509835 | 0.80 | ENPP1 (0.50) | P2RY1ENPP1P2RX1P2RX3P2RY2 | |
| SCHEMBL8343857 | 0.79 | HDAC6 (0.38) | ENPP1POLBPOLGPNP | |
| SCHEMBL76055 | 0.79 | POLG (0.62) | POLBPOLGPNP | |
| SCHEMBL443837 | 0.78 | POLG (0.47) | POLBPOLGPNP | |
| SCHEMBL16180228 | 0.78 | POLG (0.47) | POLBPOLGPNP | |
| SCHEMBL101894 | 0.77 | PNP (0.61) | POLBPOLGPNP | |
| SCHEMBL5977646 | 0.76 | PNP (0.47) | POLBPOLGPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979492-B1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | PASTEUR INSTITUT (FR) | 2014-10-29 | — | — | EP | claimed |
| EP-1979492-B1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | PASTEUR INSTITUT (FR) | 2014-10-29 | — | — | EP | disclosed |
| US-8541206-B2 | Differential amplification of mutant nucleic acids by PCR in a mixture of nucleic acids | INSTITUT PASTEUR (FR) | 2013-09-24 | — | — | US | disclosed |
| US-20110003282-A1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR (FR) | 2011-01-06 | — | — | US | disclosed |
| US-20100184017-A1 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR | 2010-07-22 | — | — | US | disclosed |
| EP-1979492-A2 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR (FR) | 2008-10-15 | — | — | EP | disclosed |
| WO-2007091125-A2 | DIFFERENTIAL AMPLIFICATION OF MUTANT NUCLEIC ACIDS BY PCR IN A MIXTURE OF NUCLEIC ACIDS | INSTITUT PASTEUR (FR) | 2007-08-16 | — | — | WO | disclosed |
| US-20070154892-A1 | Differential amplification of mutant nucleic acids by PCR in a mixure of nucleic acids | INSTITUT PASTEUR (FR) | 2007-07-05 | — | — | US | disclosed |